Vampire Crawlers’ core gameplay loop can feel repetitive, but Relics introduce unique modifiers that add variety and strategic depth. These modifiers range from minor buffs to overpowered effects, and players can toggle them on or off as desired.

To access these Relics, you must first unlock them by progressing through the game. Below is a complete breakdown of every Relic, including the stages required to unlock them and their effects.

How to Unlock and Use All Vampire Crawlers Relics

Every Relic in Vampire Crawlers is unlocked by reaching specific stages in the game. The following table outlines each Relic, the stage needed to unlock it, and how it functions:

RelicUnlock StageHow It Works
Bomba InfernaleDairy PlantAutomatically vaporizes all enemies on the first floor if the dungeon was previously cleared.
Combo StackTutorialPlay cards in ascending mana cost to create a combo multiplier.
Gem HammerMad ForestAdds gems to cards.
Grim GrimoireLibrary West WingDisplays a list of discovered weapon evolutions in the pause menu.
Guiding LightInlaid LibraryShows the location of breakable light sources on the map.
Lapidary LoupeGallo TowerAllows changing the spawn rate of specific gems to seal them.
Milky Way MapN/ADisplays the positions of enemies on the map.
OvenkiltSecret RelicTriggers overkill on the last enemy across all encounters, but gold from chests is no longer obtained.
OverkillTeeny BridgeAllows continued attacks on defeated bosses to earn more gold.
PolentirFurious ForestUnlocks the Arcana Tent.
RandomazzoLibrary SanctumArcana events are added to dungeons.
RilevatoreCurd RefineryShows the effect of weapons on enemies.
Stardust AnvilTeeny BridgeUnlocks the Blacksmith's Workshop.
Sorceress' TearsGallo TowerIncreases the general speed of the game.
Ultimate Ultra OverkillN/ARaises the damage cap of the Overkill Relic to 5,000.

Additional Tips for Maximizing Relics in Vampire Crawlers

Unlocking Relics is only part of the strategy. To further enhance your gameplay, consider unlocking all 21 characters, as each offers unique in-game effects. While some characters are easier to obtain, completing specific tasks during runs will unlock them all.

For players aiming to optimize their runs, experimenting with different Relic combinations can lead to powerful synergies. Whether you prefer high-risk, high-reward setups or balanced modifiers, the Relics system provides the flexibility to tailor your experience.